2010-2018年盐城市城镇地区恶性肿瘤流行现状及趋势分析

Analysis of the prevalence and trend of cancer in urban areas of Yancheng between 2010 and 2018

目的分析2010-2018年盐城市城镇地区恶性肿瘤流行现状和变化趋势,为政府制定恶性肿瘤防控政策提供科学依据。方法采用2021年盐城市疾病预防控制中心收集并质控后的盐城市城镇地区恶性肿瘤登记资料,计算粗发病率、粗死亡率、年龄别发病率、年龄别死亡率、中国人口标化率(中标率)、世界人口标化率(世标率)、0~74岁累积率、35~64岁截缩率等指标;采用Joinpoint软件计算2010-2018年盐城市城镇地区恶性肿瘤发病率和死亡率的年度变化百分比(annual percent change,APC)及95%CI。结果2010-2018年盐城市城镇地区恶性肿瘤粗发病率为309.62/10万,中标率为193.08/10万,0~74岁累积发病率为22.40%,35~64岁截缩率289.73/10万;同期粗死亡率为209.88/10万,中标率为125.78/10万,0~74岁累积发病率为13.83%,35~64岁截缩率141.45/10万。2010-2018年盐城市城镇地区恶性肿瘤发病和死亡水平无明显上升趋势,发病和死亡中标率的APC分别为2.21%(95%CI-0.40%~4.88%)和-1.04%(95%CI-2.77%~0.73%)。2010-2018年盐城市城镇地区恶性肿瘤的年龄别发病率和死亡率均随着年龄的增长而升高,在80~84岁组达到高峰,分别为1811.27/10万和1965.35/10万。胃癌、肺癌、食管癌、乳腺癌和肝癌是盐城市城镇居民最常见的恶性肿瘤,肺癌、胃癌、食管癌、肝癌和结直肠癌是其主要的肿瘤死因。结论盐城市城镇地区恶性肿瘤呈高发状态,男性及中老年人是恶性肿瘤高危人群,以胃癌为首的消化道肿瘤应作为盐城市城镇地区肿瘤防治工作重点。

Objective To analyze the prevalence and trends of cancer in urban areas of Yancheng between 2010 and 2018,and to provide scientific evidence for the government to formulate cancer prevention and control policies.Methods The Cancer Registry data of urban areas in Yancheng were collected and quality controlled by the Centers for Disease Control(CDC)and the 2021 prevention of the Chinese.The crude incidence rate,crude mortality rate,age-specific incidence rate,age-specific mortality rate,standardized rate of the Chinese population(success rate),standardized rate of the world’s population(world standard rate),cumulative rate of 0-74 year olds,and the truncated rate of 35-64 year olds were calculated.The annual percent change(APC)and the 95%CI of cancer incidence or mortality in urban Yancheng between 2010 and 2018 were analyzed using Joinpoint software.Results Between 2010 and 2018,the crude incidence rate was 309.62 per 100,000,the successful bid rate was 193.08 per 100,000,the cumulative incidence rate of 0-74 year olds was 22.40%,and the truncation rate of 35-64 year olds was 289.73 per 100,000;During the same period,the crude mortality rate was 209.88 per 100,000,the successful bid rate was 125.78 per 100,000,the cumulative incidence rate of 0-74 year olds was 13.83%,and the truncation rate of 35-64 year olds was 141.45 per 100,000.There was no significant upward trend in the incidence and mortality of malignant tumors in urban areas of Yancheng between 2010 and 2018.The APC for the successful rate of cancer and mortality was 2.21%(95%CI-0.40%-4.88%)and-1.04%(95%CI-2.77%-0.73%),respectively.Between 2010 and 2018,the age-specific incidence and mortality of malignant tumors in urban areas of Yancheng increased with the increase in age,and peaked in the 80-year-old group at 1811.27 per 100,000 and 1965.35 per 100,000,respectively.Cancer of the stomach,lung,esophagus,breast,and liver were the most common cancers among urban residents in Yancheng,while lung,stomach,esophagus,liver,and colorectal cancers were the leading causes of cancer-associated deaths.Conclusions A high incidence of malignant tumors is shown in urban areas of Yancheng.Male and middle-aged residents are shown to be a high-risk population for malignant tumors in Yancheng.