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宫颈癌患者血浆SCCA、FIB的水平变化及其临床意义 被引量:1

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摘要 目的探讨宫颈癌患者血浆鳞状细胞癌抗原(SCCA)、血浆纤维蛋白原(FIB)水平变化及临床意义。方法选取2018年3月至2019年12月株洲市三三一医院收治的56例宫颈癌患者作为宫颈癌组,按宫颈癌分级标准,分为中宫颈癌Ⅰ级(10例)、Ⅱ级(15例)、Ⅲ级(20例)、Ⅳ级(11例)。选取同期52例健康体检者作为对照组及52例宫颈良性病变患者作为宫颈良性病变组。检测并观察三组血浆SCCA、FIB浓度。结果宫颈癌组患者血浆SCCA、FIB浓度均显著高于宫颈良性病变组及对照组,差异有统计学意义(P<0.05)。宫颈癌早期患者血浆SCCA、FIB浓度显著低于晚期患者,其中Ⅰ期低于Ⅱ期,Ⅱ期低于Ⅲ期,Ⅲ期患者低于Ⅳ期,差异有统计学意义(P<0.05)。术后1周,FIB和SCCA浓度显著低于术前,差异有统计学意义(P<0.05)。结论血浆SCCA和FIB水平能准确诊断宫颈癌,同时且根据其浓度变化,能有效评估患者病情严重程度,且能预测术后治疗效果。
作者 刘秋菊
出处 《慢性病学杂志》 2020年第10期1547-1548,1551,共3页 Chronic Pathematology Journal
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