小花鬼针草中1个新的聚炔和1个新的异烟酸葡萄糖酯苷

A new polyacetylene and a new isonicotinic acid glucoside from Bidens parviflora Willd.

采用硅胶、聚酰胺、Sephadex LH-20及HPLC对小花鬼针草80%乙醇提取物的乙酸乙酯部位进行分离纯化,共得到11个单体化合物,根据其理化性质及波谱数据分别鉴定为(2S)-十三烷-(11E)-一烯-3,5,7,9-四炔-1,2,13-三醇(1)、吡啶-4-甲酰-O-β-D-吡喃葡萄糖酯苷(2)、海生菊苷(3)、trichocarpine(4)、奥卡宁-4-甲醚-3′-O-β-D-吡喃葡萄糖苷(5)、奥卡宁-4-甲醚-4’-O-β-D-(6′′-乙酰基)-葡萄糖苷(6)、Z-6-O-(6″-O-p-香豆酰基-β-D-吡喃葡萄糖基)-6,7,3′,4′-四羟基橙酮(7)、槲皮素-3-O-α-L-阿拉伯糖苷(8)、金丝桃(9)、(3S)-十四烷-(6E,12E)-二烯-8,10-二炔-1,14-二醇-3-O-β-D-葡萄糖苷(10)和鬼针聚炔苷B(11)。其中化合物1和2为新的化合物,化合物4和8为首次从该属植物中分离得到,化合物5~7、10和11为首次从该植物中分离得到。

The ethyl acetate fraction of 80%ethanol extract from Bidens parviflora Willd.was isolated and purified by silica,polyamide,Sephadex LH-20 and HPLC.A total of eleven compounds were isolated and identified by physicochemical properties and spectral data as(2 S)-11 E-tetradecene-3,5,7,9-tetrayne-1,2,13-triol(1),pyridine-4-formyl-O-β-D-glucopyranoside(2),maritimein(3),trichocarpine(4),okanin-4-methyl ether-3′-O-β-D-glucopyranoside(5),okanin-4-methyl ether-4′-O-β-D-(6″-acetyl)-glucopyranoside(6),(Z)-6-O-(4″-acetyl-6″-O-p-coumaroyl-β-D-glucopyranosyl)-6,7,3′,4′-tetrahydroxyaurone(7),quercetin-3-O-α-L-arabinoside(8),hyperoside(9),(3 S)-(6 E,12 E)-tetradecadiene-8,10-diyne-1,14-diol-3-O-β-D-glucopyranoside(10),bipinnata polyacetyloside B(11).Compounds 1 and 2 are new compounds,compounds 4 and 8 were isolated from the genus Bidens for the first time,compounds 5-7,10 and 11 were isolated from this plant for the first time.