各国药典核磁共振波谱法通则概况及其应用

Overview and application of nuclear magnetic resonance spectroscopy method in pharmacopoeias

近年来,各国药典陆续修订核磁共振波谱法通则,以适应核磁共振波谱技术的发展,并扩大其在生药、化学药品、生物制品、药用辅料和药包材等通则和品种标准中的应用。本文介绍了各国药典核磁共振波谱法通则概况及在品种标准中的应用现状,旨在为中国药典0441核磁共振波谱法通则的修订和核磁共振波谱法在我国制药领域中的进一步应用提供参考。

In recent years,the general chapters of nuclear magnetic resonance spectroscopy(NMR)method have been revised successively in the pharmacopoeias to adapt to the development of NMR method and to expand its application in the general chapters and monographs of crude drugs,chemical drugs,biological products,pharmaceutical excipients and packaging materials.In this paper,the general chapters of nuclear magnetic resonance spectroscopy in pharmacopoeias and their application in monographs were introduced,aiming to provide a reference for the revision of the Chinese Pharmacopoeia 0441 general chapter of Nuclear Magnetic Resonance Spectroscopy and the further application of NMR method in the pharmaceutical industry in China.