火针联合埋线治疗Hp相关性慢性非萎缩性胃炎临床观察

Clinical Effect of Fire Acupuncture Combined with Embedding Wire in the Treatment of HP Related Chronic Non-atrophic Gastritis

目的:采用RCT实验,比较火针联合埋线疗法和根除Hp的四联疗法治疗Hp(+)慢性非萎缩性胃炎的临床疗效。方法:采用随机分组法,将60例符合诊断标准的患者平均分为两组。实验组采用火针+埋线疗法,对照组采用根除Hp的四联治疗方法。结果:(1)临床疗效:针灸干预的实验组和西药干预的对照组的总有效率分别是96.7%和76.7%,组内和组间比较,差异有统计学意义(P<0.05);(2)临床症状积分:采用两种治疗方法分别对两组患者进行干预后,全部受试者的5种主症积分的组内比较,差异均有统计学意义(P<0.05);组间比较,差异有统计学意义(P<0.05);(3)内镜下改善率:两组的镜下改善率均为83.3%,两组组内前后对比差异有统计学意义(P<0.05);组间比较,差异无统计学意义(P>0.05);(4)Hp转阴率:实验组和对照组的转阴率分别为73.3%和96.7%,两组治疗前后和组间比较,差异均具有统计学意义(P<0.05)。结论:(1)火针+埋线疗法临床和远期疗效更好,可明显缓解患者胃脘疼痛、脘腹胀满、嗳气、纳呆食少等症状,但四联疗法更能改善患者反酸的症状和根除实验室指标Hp;(2)两种疗法能够同等程度地改善镜下表现。

Objective:To compare the clinical effect of combined fire acupuncture and embedding therapy with RCT in the treatment of chronic non atrophic gastritis with Hp(+).Methods:According to the principle of randomization,60 patients who met the diagnostic criteria were divided into two groups on average.The experimental group was treated with fire needle plus embedding wire,and the control group was treated with four ways of Hp eradication.Results:(1)Clinical effect:the total effective rate of acupuncture intervention group and Western medicine intervention control group was 96.7%and 76.7%,respectively.The difference was statistically significant between the two groups(P<0.05).(2)Clinical symptom score:the two different treatment methods of Chinese and Western medicine respectively did the prognosis of the two groups.The comparison of five main symptom scores among all subjects was statistically significant(P<0.05),there was significant difference between the groups(P<0.05)(3)Endoscopic improvement rate:the improvement rate of the two groups was 83%,the difference between the two groups was statistically significant,both groups had statistical significance,both groups had statistical significance the difference between the two groups was not statistically significant,and the rate of Hp was 73.3%and 96.7%respectively in the experimental group and the control group,respectively.The difference between the two groups was statistically significant(P<0.05).Conclusion:(1)Fire needle with thread embedding therapy has better clinical and long-term effects,and is better at relieving patients with gastric pain,abdominal distension,belching,and lack of appetite.Quadruple therapy is better at improving patients’acid reflux symptoms and eradicating the laboratory Index Hp;(2)The two therapies can improve the microscopic performance to the same extent.