羌活炮制工艺研究

Study on Processing Technology of Qianghuo(Notopterygii Rhizoma et Radix)

目的:优化及量化羌活饮片炮制工艺参数,为工业化生产提供依据。方法:以切片情况、吸水增重率为评价指标,单因素试验考察吸水量、闷润温度、闷润时间;以浸出物含量百分率、羌活醇、异欧前胡素、挥发油为评价指标,正交试验优化饮片厚度、铺层厚度、鼓风干燥温度、翻动次数对羌活饮片质量的影响。首先将羌活原药材除去杂质泥沙,淋洗5min,沥干,再置30℃培养箱中闷润2h。结果:最佳炮制工艺为40℃干燥,切4mm厚片,堆放1cm厚,翻动2次。结论:羌活饮片与羌活原药材比较,其挥发油、浸出物、羌活醇、异欧前胡素评价指标的量值传递率均达到90%以上,表明优选出来的羌活饮片炮制工艺科学、合理、稳定、可靠。

Objective:To optimize and quantify the process parameters of Qianghuo(Notopterygii Rhizoma et Radix)yinpian to provide the basis for industrialization.Methods:With section condition,weight gain rate of water absorption as the indices of process evaluation,designing single factor experiment to investigate the water absorption,the moistening temperature and the moistening time.And with content percentage of extract,notopterol,isoimperatorin and essential oil as the indices of process evaluation,designing orthogonal experiment to optimize the effects of slice thickness,layer thickness,air drying temperature and turning times on the quality of Qianghuo(Notopterygii Rhizoma et Radix)yinpian.First,remove the impurities and sediment from Qianghuo(Notopterygii Rhizoma et Radix)herbs,wash Qianghuo(Notopterygii Rhizoma et Radix)herbs for 5 min,drain Qianghuo(Notopterygii Rhizoma et Radix)herbs,and then place Qianghuo(Notopterygii Rhizoma et Radix)herbs in an incubator at 30℃for 2 hours.Results:The best processing technology was drying at 40℃,cutting 4 mm thick slices,stacking 1 cm thick,turning twice.Conclusion:Compared with Qianghuo(Notopterygii Rhizoma et Radix)herbs,the transfer rate of essential oil,extract,notopterol and isoimperatorin of Qianghuo(Notopterygii Rhizoma et Radix)yinpian were all over 90%,which indicated that the optimized processing technology of Qianghuo(Notopterygii Rhizoma et Radix)yinpian was scientific,reasonable,stable,reliable and feasible.