新疆地区类风湿关节炎主要中医证型分布规律研究

Study on Distribution Law of Main Types of Traditional Chinese Medicine Syndromes of Rheumatoid Arthritis in Xinjiang

目的:调查研究新疆地区类风湿关节炎(RA)的主要中医证型的流行病学分布规律,为该病临床辨证论治提供参考依据。方法:采集某院收治且确诊为类风湿关节炎的患者病历资料223份。完善电子数据库,使用SPSS 22.0软件统计分析类风湿关节炎主要中医证型在性别、年龄及病程等方面的分布规律。结果:类风湿关节炎各证型分布存在统计学差异(P<0.05)。类风湿关节炎各证型在性别(P=0.255)、病程(P=0.365)方面差异不明显,而在年龄(P=0.014)方面存在统计学差异。在年龄方面:年龄<40岁的患者,证型分布依次为:风湿痹阻证>痰瘀痹阻证>寒湿痹阻证>肝肾不足证>湿热痹阻证;40~60岁的患者,证型分布为:风湿痹阻证>痰瘀痹阻证>湿热痹阻证>肝肾不足证>寒湿痹阻证>气血两虚证>瘀血阻络证>气阴两虚证;年龄>60岁的患者,证型分布为:痰瘀痹阻证>肝肾不足证>湿热痹阻证>寒湿痹阻证>风湿痹阻证>气阴两虚证证>气血两虚证=瘀血阻络证。结论:新疆地区类风湿关节炎主要证型以风湿痹阻证为主,其次为痰瘀痹阻证、肝肾不足证、湿热痹阻证、寒湿痹阻证,气血两虚证、瘀血阻络证与气阴两虚证相对较少。年龄可能对新疆地区类风湿关节炎中医证型分布有较大的影响。

Objective:To study and analyze the epidemiological distribution of the main TCM syndromes in rheumatoid arthritis(RA)in Xinjiang,and to provide a reference for the study of clinical syndrome differentiation.Methods:223 cases of patients who were diagnosed as rheumatoid arthritis in the Xinjiang Uygur Autonomous Region Chinese Medicine Hospital were collected.A database was established and analyzed with SPSS 22.0,it mainly analyze the distribution pattern of the main TCM syndromes of rheumatoid arthritis in terms of gender,age and course of the disease.Results:The distribution of rheumatoid arthritis was significantly different(P<0.05).There were no significant differences in the types of rheumatoid arthritis in terms of gender(P=0.255)and course of the disease(P=0.365),but there were significant differences in age(P=0.014).In terms of age:For patients younger than 40 years old,the distribution of syndrome types(from high to low)is rheumatism obstruction syndrome,phlegm and stasis obstruction syndrome,cold and dampness obstruction syndrome,liver and kidney deficiency syndrome,and damp-heat obstruction syndrome;For patients between the ages of 40 and 60,the syndrome types(high to low)are rheumatism obstruction syndrome,phlegm and stasis obstruction syndrome,damp heat obstruction syndrome,liver and kidney deficiency syndrome,cold and dampness obstruction syndrome,qi and blood Two deficiency syndromes,blood stasis obstruction syndrome,qi and yin deficiency syndromes.For patients older than 60 years old,the syndrome type(high to low)are Phlegm and blood stasis syndrome,liver and kidney deficiency syndrome,dampness and heat bi syndrome,cold and wet bi syndrome,rheumatism bi syndrome,qi and Yin deficiency syndrome,qi and blood deficiency syndrome=blood stasis syndrome.Conclusion:The main syndrome types of rheumatoid arthritis in Xinjiang are rheumatoid arthritis obstruction syndrome,followed by phlegm and stasis obstruction syndrome,liver and kidney deficiency syndrome,damp heat obstruction syndrome,and cold dampness obstruction syndrome.There are relatively few qi and blood deficiency syndromes,stasis and blood stasis syndrome and qi and yin deficiency syndromes.Age may be one of the main factors affecting the distribution of rheumatoid arthritis syndromes in Xinjiang.