一种导尿管表面抗菌涂层制备方法应用研究

Study on the Application of a Method for Preparing Antibacterial Coating on the Surface of Catheter

研究了一种导尿管表面抗菌涂层的制备方法。由表面自由基引发聚合和层层自组装方法相结合,具有操作简单、表面结构可控和抗菌能力持久的优势。利用环氧树脂和自由基引发剂对导尿管表面的预处理,在导尿管表面引发丙烯酸自由基聚合,第一层带有阴离子层聚丙烯酸;利用阳离子层的聚咪唑盐和阴离子层的透明质酸层层自组装构筑抗菌表面。

A preparation method of antibacterial coating on the surface of urinary catheter was studied.The combination of surface free radical-initiated polymerization and layer-by-layer self-assembly method has the advantages of simple operation,controllable surface structure and long-lasting antibacterial ability.Using epoxy resin and free radical initiator to pretreat the surface of the urinary catheter to initiate acrylic acid free radical polymerization on the surface of the urinary catheter.The first layer has an anionic layer of polyacrylic acid;the use of cationic layer of polyimidazole salt and anionic layer Layers of hyaluronic acid self-assemble to build an antibacterial surface.