光催化烯烃α-酰化反应

α-Acylation of Olefins via Photocatalysis

烯烃酰化反应被广泛用于制备结构丰富且高附加值的酮、醛、羧酸及其衍生物.多组分串联N-杂环卡宾催化和过渡金属催化的烯烃α-酰化反应具有高效、高选择性的优点,然而受限的反应模式和底物范围限制了反应的发展.光催化烯烃α-酰化反应突破了这一限制,具有更丰富、更广泛的底物适用范围.以研究策略为线索,对这一快速的研究进展进行了总结和展望.

The cheap and readily available olefin substrates have received much attention for the synthesis of structurally rich and high value-added ketones,aldehydes,carboxylic acids and their derivatives viaα-acylation.Multicomponent tandemα-acylation of olefins achieves high efficiency and selectivity by N-heterocyclic carbene or transition metal catalysis,albeit with narrow reaction modes and substrates.Rapid growth of photocatalysis in organic transformation has introduced new methodologies to undergo theα-acylation of olefins with broad substrate scope.The research progress and prospect for the future development in this active research field is highlighted.