Noncarrier embryo selection and transfer in preimplantation genetic testing cycles for reciprocal translocation by Oxford Nanopore Technologies

Balanced reciprocal translocation is one of the most common chromosome abnormalities,with an incidence of approximately 1in every 500 newborns(Mackie Ogilvie and Scriven,2002).Most balanced reciprocal translocation carriers have no observable phenotype because there is no loss or gain of genetic material(Ogilvie et al.,2001).However,the carriers have a risk of infertility.