30例多发性硬化的临床及MRI表现

Clinical and MRI manifestations of 30 patients with multiple sclerosis

[背景]提高对多发性硬化的MRI特征表现的认识及临床诊断水平.[病例报告]回顾性分析30例多发性硬化患者的临床表现及MRI特征,结果见本组患者临床上均具有反复发作病史,其中病灶分布于大脑半球皮质下白质区、半卵圆中心、侧脑室旁24例,垂直于侧脑室16例,脊髓颈段及中上胸段6例;病灶直径3~5 cm;病灶形态呈团块状21例,条带状9例;病灶T1WI低信号,T2WI高信号,新发病灶及活动期病灶强化后均呈斑片状、环状或线状强化,陈旧性病灶不强化.[讨论]根据典型的临床表现及MRI特有征象可对多发性硬化患者进行确诊并制定有效的治疗方案.

BACKGROUND To improve the understanding of MRI manifestations and clinical diagnosis level of multiple sclerosis.CASE REPORTS The clinical manifestations and MRI features of 30 patients with multiple sclerosis were retrospectively analyzed.The results showed that all the patients had a history of recurrent attacks.Among them,the lesions of 24 cases were distributed in the subcortical white matter area of the cerebral hemisphere,the centrum semiovale and the lateral ventricle,the lesions of 16 cases were perpendicular to the lateral ventricle,and the lesions of 6 cases were located in the cervical and middle and upper thoracic segments of spinal cord.The diameter of the lesions was 3 to 5 cm.The morphology of the lesions was lumpy in 21 cases and banded in 9 cases.The lesions showed low signal intensity on T1 WI and high signal intensity on T2 WI.After enhancement,the new lesions and active lesions showed patchy,ring or linear enhancement,while the old lesions did not show enhancement.DISCUSSION According to the typical clinical manifestations and MRI features,we can diagnose the patients with multiple sclerosis and make the effective therapeutic regimen.