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急性ST段抬高型心肌梗死患者发生左心室附壁血栓的相关因素分析 被引量:6

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摘要 目的探讨急性ST段抬高型心肌梗死(STEMI)患者并发左心室附壁血栓(LVT)的影响因素。方法入选2015年1月至2019年12月在本院就诊的STEMI患者151例,根据是否并发LVT分为LVT组(31例)和非LVT组(120例),观察两组患者临床基线资料、冠脉病变情况、手术相关情况、实验室检查和超声心动图检查结果。结果两组患者一般临床资料,包括年龄、性别、高血压、糖尿病和高脂血症、吸烟、饮酒史比较差异无统计学意义(P>0.05)。LVT组患者发病至入院时间长于非LVT组,差异有统计学意义(P<0.05),前壁心肌梗死比例高于非LVT组(P<0.001),行直接经皮冠状动脉介入治疗(PCI)比例低于非LVT组(P<0.001),左前降支(LAD)病变的比例高于非LVT组(P<0.05),纤维蛋白原水平高于非LVT组(P<0.05),超声心动图检查结果LVT组左心室射血分数(LVEF)低于非LVT组,左心室舒张末内径(LVIDD)大于非LVT组,室壁瘤形成比例高于非LVT组(P<0.001)。两组患者c TnI峰值、CK-MB峰值、平均血小板体积(MPV)、血小板/淋巴细胞比值(PLR)、中性粒细胞/淋巴细胞比值(NLR)水平差异无统计学意义(P>0.05)。对单因素分析中有统计学意义的因素进行logistics回归分析,结果显示直接PCI(OR=0.23,95%CI:0.073-0.723)、LVEF水平(OR=0.892,95%CI:0.819-0.973)、室壁瘤形成(OR=29.64,95%CI:2.894-303.547)是STEMI后发生LVT的独立影响因素,直接PCI、LVEF是LVT的独立保护因素,室壁瘤形成是LVT的独立危险因素。结论发病至入院时间、前壁心肌梗死、直接PCI、LAD病变、纤维蛋白原、LVEF、LVIDD、室壁瘤形成是STEMI患者并发LVT的相关因素。
出处 《心血管病防治知识(学术版)》 2020年第36期15-18,共4页 Prevention and Treatment of Cardiovascular Disease
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