羊毛弯曲及毛囊发育相关生物学机制研究进展

Research Progress on Biological Mechanisms Related to Wool Bending and Hair Follicle Development

羊毛弯曲是影响羊毛品质高低的关键因素之一,毛股弯曲的减少以及毛股由紧实变得蓬松会导致羊毛品质下降,从而影响皮毛价值。毛囊是调控毛发生长的皮肤附属器官,对于毛发弯曲形状的形成具有重要作用。近年来,有关羊、小鼠等动物毛发纤维弯曲形成的相关研究以及毛囊发育调控等取得了一定进展。本文介绍了羊毛纤维结构的特点,阐述了毛囊发育相关重要调控信号通路及其对毛发弯曲的影响,最后,基于羊毛弯曲相关的基因和蛋白的研究进展进行综述。通过对羊毛弯曲及毛囊发育相关生物学机制进行总结,以期对羊毛弯曲及毛囊发育的相关分子机制的研究提供理论依据,同时也对改良羊毛弯曲性状的工作提供一些参考。

Wool curvature is one of the key factors affecting wool quality.The decrease of wool curvature and the change of wool strand from compactness to fluffy will lead to the decline of wool quality,which will affect the value of fur.Hair follicle is a skin accessory organ that regulates hair growth and plays an important role in the formation of curvature of hair.In recent years,some progress had been made in the study of curvature formation of hair fibers in sheep,mice and other animals,as well as in the regulation of hair follicle development.In this paper,the characteristics of wool fiber structure were introduced,and the important regulatory signaling pathways related to hair follicle development and their effects on hair curvature were elaborated.In summary,the research progress of wool curvature related genes and proteins were reviewed.The biological mechanism of wool curvature and hair follicle development were summarized in order to provide theoretical basis for the study of molecular mechanism of wool curvature and hair follicle development,and to provide some references for improving wool curvature characteristics.