大麻叶提取物的抗炎功效研究

Study on the Anti-Inflammatory Effect of Cannabis sativa L. Leaf Extract

通过观察以大麻叶提取物作用后斑马鱼尾鳍损伤部位巨噬细胞和中性粒细胞聚集和清除情况,研究大麻叶提取物的抗炎功效。结果表明:(1)在质量浓度1.0μg/m L和2.0μg/m L时,大麻叶提取物对斑马鱼巨噬细胞和中性粒细胞在斑马鱼尾鳍伤口处聚集有抑制作用,并相比对照具有显著性差异;(2)在质量浓度2.0μg/m L时,大麻叶提取物对斑马鱼巨噬细胞和中性粒细胞在斑马鱼尾鳍伤口处清除有促进作用,并相比对照具有显著性差异。研究证明大麻叶提取物具有良好的抗炎功效,在化妆品中具有良好的应用前景。

The anti-inflammatory effect of Cannabis sativa L.leaf extract was studied by observing the aggregation and clearance of macrophages and neutrophils in the damaged caudal fin of zebrafish after treating with Cannabis sativa L.leaf extract.The results showed that:(1)at 1.0μg/mL and 2.0μg/mL,Cannabis sativa L.leaf extract could significant inhibit the aggregation of macrophages and neutrophils in the damaged part of the tail fin of zebrafish;(2)at 2.0μg/mL,Cannabis sativa L.leaf extract could significantly promote the clearance of macrophages and neutrophils in the damaged part of the tail fin of zebrafish.Studies have proved that Cannabis sativa L.leaf extract had good anti-inflammatory effect and broad application prospect in cosmetics.