358例发热待查患者的临床特征分析

Analysis of clinical characteristics of 358 patients with fever of unknown origin

目的 分析358例发热待查(FUO)患者临床特征,为发热待查的临床诊治提供参考。方法 回顾性分析新疆医科大学第一附属医院自2019年1月1日-2020年1月1日收治的358例发热待查患者,将病因分为感染性疾病(259例)、非感染性发热(76例)及诊断不明(23例)3类,分析其临床特点。结果 非感染性疾病组的住院天数(16.21±11.74)较感染性疾病组(9.82±6.51)更长,差异有统计学意义(P <0.05)。感染性疾病中以细菌性感染212例(81.9%)最常见,非典型病原体感染中布氏杆菌病9例(2.51%)、结核菌感染例41例(11.45%)。非感染性疾病中以未分型结缔组织病39例(51.3%)更为常见。结论 FUO患者在诊疗过程中要根据流行病史、临床表现、体征及实验室指标等进行综合分析,以尽早明确诊断。

Objective The clinical characteristics of 358 patients with fever to be investigated(FUO)were analyzed to provide reference for the clinical diagnosis and treatment of fever to be investigated.Methods A retrospective analysis of 358 patients with fever who were admitted to the First Affiliated Hospital of Xinjiang Medical University from January 1,2019 to January 1,2020.They were divided into 3 categories:infectious diseases(259 cases),non-infectious fever(76 cases)and undiagnosed(23 cases),and their clinical characteristics were analyzed.Results The number of days in hospital of the non-infectious disease group was(16.21±111.74)longer than that in the infectious disease group(9.82±16.51),and the difference was statistically significant(P<0.05).Among infectious diseases,212 cases(81.9%)of bacterial infection were the most common.9 cases of brucellosis(2.51%)and 41 cases of tuberculosis infection(11.45%)were found in atypical pathogens.Non-infectious diseases were more common in 39 cases(51.3%)of unclassified connective tissue diseases.Conclusion FUO patients should be comprehensively analyzed according to epidemic history,clinical manifestations,signs and laboratory indicators in the process of diagnosis and treatment,so as to make a clear diagnosis as soon as possible.