SAA联合CRP及WBC计数检测在小儿肺炎鉴别诊断中的应用

Study on SAA combined with CRP and WBC count detection in differential diagnosis of pediatric pneumonia

目的探讨多项指标联合检测对小儿肺炎的鉴别诊断、疗效评价的作用。方法回顾性分析本院2018年1月至2019年5月住院未经抗感染治疗的<5岁的符合入组要求的肺炎患儿共342例,细菌性肺炎178例,病毒性肺炎90例,支原体肺炎74例,对其样本进行CRP、SAA、SAA/CRP比值及WBC检测,分析各指标的诊断效能。结果CRP及WBC在细菌性肺炎组中增高最明显,SAA及SAA/CRP比值在病毒性肺炎及支原体肺炎中均增高,差异有显著性意义。结论通过ROC曲线得出,CRP及WBC可作为诊断细菌性肺炎的指标,三项指标联合检测可为临床诊断不同肺炎类型及治疗方案提供依据。

Objective To explore the role of combined detection of multiple indicators in differential diagnosis and evaluation of pediatric pneumonia.Method 342 cases less than 5 years old who underwent pneumonia and hadn’t been treated with the anti-infective treatment in the hospital from January 2018 to May 2019 were analyzed retrospectively.All cases included 178 cases with bacterial pneumonia,90 cases with viral pneumonia,74 cases with mycoplasma pneumonia.CRP,SAA,SAA/CRP ratio and WBC test were performed on the samples,and the diagnostic efficacy of each index was analyzed.Results CRP and WBC increased the most obviously in all cases.The ratio of SAA and SAA/CRP increased in both viral pneumonia group and mycoplasmal pneumonia group.The difference was significant.Conclusion According to the ROC curve,CRP and WBC can be used as indicators for the diagnosis of bacterial pneumonia.The combined detection of three indicators can provide a basis for clinical diagnosis of different types of pneumonia and treatment options.