乌鲁木齐地区RhD阴性无偿献血者不规则抗体筛查分析

Analysis of screening results of irregular antibodies among RhD-negative blood donors in Urumqi

目的分析乌鲁木齐地区RhD阴性无偿献血者不规则抗体阳性率,探讨对RhD阴性献血者进行抗体筛查的必要性。方法采用盐水介质法和抗人球介质法对乌鲁木齐地区3296例无偿献血者的血液标本进行不规则抗体筛查,并对抗体筛查阳性标本鉴定其抗体特异性。结果共检出53例不规则抗体,阳性率为1.61%,女性不规则抗体阳性率率(1.94%)高于男性(1.09%),差异具有统计学意义(P<0.05)。结论采供血机构有必要对RhD阴性献血者进行抗体筛查,防止含有不规则抗体的血液进入患者体内而引起输血反应。

Objective To analyze the positive rate of irregular antibodies of RhD-negative blood donors and explore the necessity of antibody screening for RhD-negative blood donors.Method The irregular antibody screening was performed on the blood samples of 3296 blood donors in Urumqi by saline medium method and anti-human globulin method,and the antibody specificity of the positive samples was identified.Results A total of 53 cases of irregular antibodies were detected,and the positive rate was 1.61%.The positive rate of irregular antibodies in female donors(1.94%)was higher than that in male donors(1.09%),and the difference was statistically significant(P<0.05).Conclusion Irregular antibody screening for RhD-negative blood donors was necessary for blood transfusion services,which can prevent the irregular antibodies from entering the patient’s body and causing transfusion reaction.