地佐辛用于下肢骨折患者椎管内麻醉前的镇痛作用探讨

Analgesic effect of dezocine before spinal anesthesia in patients with lower limb fracture

目的对下肢骨折患者在椎管内麻醉前应用地佐辛,以此探讨地佐辛在下肢骨折手术中的镇痛作用。方法选择2016年2月至2018年2月就诊于新疆生产建设兵团第四师医院100例下肢骨折患者。随机数字表法分为对照组与研究组,均予以椎管内麻醉处理,其中,对照组麻醉之前肌注0.9%氯化钠注射液(2 mL),研究组则肌注5 mg地佐辛。观察组间的并发症发生率(尿潴留率、恶心呕吐率)、不同时间点(安静平卧位时、体位摆放时、麻醉成功后)的镇静效果评分、镇痛效果评分。结果对照组与研究组在镇痛方面的安静平卧位时、体位摆放时、麻醉成功后的数据指标差异存在统计学意义,P<0.05;研究组与对照组在安静平卧位时、体位摆放时、麻醉成功后各个时间点的镇静效果评分数据对比中发现不存在差异性,P>0.05。结论对下肢骨折患者在椎管内麻醉前应用地佐辛,可以得到显著的镇痛效果,且不会增加患者的并发症发生率。

Objective To investigate the analgesic effect of dezocine in patients with lower extremity fractures before spinal canal anesthesia.Methods A total of 100 patients with lower extremity fractures who were treated in our hospital from February 2016 to February 2018 were selected.The random number table method was divided into the control group and the study group,and they were treated with spinal anesthesia.Among them,the control group was intramuscularly injected with 0.9%sodium chloride injection(2 m L),and the research group was intramuscularly injected with 5 mg dezocine.The incidence of complications(urinary retention rate,nausea and vomiting rate),sedation effect scores and analgesic effect scores at different time points(when resting in supine position,during postural placement,and after successful anesthesia)were observed between the observation groups.Results There were statistically significant differences between the control group and the study group in the analgesic position,position,and after successful anesthesia,P<0.05;the study group and the control group were in the supine position.No difference was found in the comparison of the sedation effect score data at various time points after the body position was placed and after the successful anesthesia,P>0.05.Conclusion Applying dezocine to patients with lower extremity fractures before spinal canal anesthesia can achieve significant analgesic effects without increasing the incidence of complications for patients.