2017—2022年响水县手足口病流行病学和病原学特征分析

Analysis of epidemiological and aetiological characterisation of hand,foot and mouth disease from 2017 to 2022,Xiangshui County

目的分析盐城市响水县2017—2022年手足口病(HFMD)流行病学及病原学特征,为制订其防控策略提供依据。方法采用描述性流行病学的方法对2017—2022年于“中国疾病预防控制信息系统”的“传染病报告信息管理系统”报告的盐城市响水县HFMD资料进行分析。结果2017—2022年盐城市响水县累计报告HFMD 1024例,年平均发病率为27.54/10万。2018年发病率最高,2020—2022年呈下降趋势;不同乡镇之间HFMD发病率差异有统计学意义;>1~2岁组发病率最高,为977.19/10万。不同年份优势毒株亦有不同,但总体以柯萨奇病毒6型(CV-A6)为流行优势株。结论响水县手足口病流行具有明显的人群性以及地区性,流行优势毒株为CV-A6。

Objective This study explored the epidemiological and pathogenetic characteristics of hand,foot and mouth disease(HFMD)in Yancheng City,Xiangshui County,from 2017 to 2022,to provide a foundation for the development of effective prevention and control strategies.Methods A descriptive epidemiological method was used to analyse data on HFMD cases retrieved from China’s disease prevention and control information system in 2017-2022.Results Between 2017 and 2022,1024 HFMD cases were reported,thus indicating an average annual incidence rate of 27.54 per 100000.The incidence peaked in 2018,and a consistent decrease was observed in 2020-2022.The incidence rates among regions showed statistically significant differences.The 1-year-old age group had the highest incidence,at 977.19 per 100000 people.According to pathogenicity testing,the dominant strains varied from year to year,but Coxsackievirus 6(CV-A6)was generally the dominant strain in circulation.Conclusion The HFMD epidemic in Xiangshui County exhibited distinct population and regional characteristics.The consistently dominant epidemic strain was identified as CV-A6.