事件相关电位P300在认知障碍相关疾病的临床应用

Clinical application of event-related potential P300 in cognitive impairment-related diseases

大部分对认知功能相关疾病的诊断主要依据临床表现和主观性较强的量表评估,对各种疾病相关的认知功能改变评估缺乏可靠、可重复性的客观指标。P300对各种疾病相关的认知功能评估提供了一种可靠且具有可重复性的客观指标,对临床疾病的认知功能损害早期诊断和早期识别具有重要的临床意义。本文主要就P300在认知功能改变相关疾病的应用作一综述,以便对各种疾病的认知改变进行早期干预治疗及预防,改善患者预后及远期生活质量。

Most of the diagnosis of cognitive function-related diseases is mainly based on clinical manifestations and subjective scales,and there is a lack of reliable and reproducible objective indicators for the assessment of cognitive function changes related to various diseases.P300 provides a reliable and reproducible objective index for the assessment of cognitive function related to various diseases,and has important clinical significance for the early diagnosis and early identification of cognitive impairment in clinical diseases.This article reviews the application of P300 in diseases related to cognitive function changes,so as to facilitate early intervention,treatment and prevention of cognitive changes in various diseases,and improve the prognosis and long-term quality of life of patients。