食管支架内镜植入在恶性食管狭窄患者治疗中的应用

Application on Endoscopic Implantation of Esophageal Stent in the Treatment of Patients with Malignant Esophageal Stenosis

目的分析食管支架内镜植入在恶性食管狭窄治疗中的应用效果。方法选取2021年1月-2022年12月本院收治的食管癌合并食管狭窄患者86例,采用随机抽样法结合纳入标准、排除标准将其随机编号1~86,研究设计对照组、观察组分别纳入奇数编号以及偶数编号患者各43例。对照组患者采用内镜下扩张探条扩张术进行治疗,观察组患者采用内镜下食管支架植入术治疗。对比分析两组患者食管狭窄处直径、食管癌专用生活质量量表评分以及相关并发症发生情况。结果手术前,狭窄直径组间比较无明显差异(P>0.05);手术后,两组患者食管狭窄直径均显著提高且观察组患者显著高于对照组(P<0.05)。手术前,食管癌专用生活质量量表评分组间比较无明显差异(P>0.05);手术后,两组患者食管癌专用生活质量量表评分均显著提高且观察组患者评分显著高于对照组(P<0.05)。并发症发生率组间比较,观察组4.65%(2/43)显著低于对照组18.60%(8/43)(P<0.05)。结论应用内镜下食管支架植入术为恶性食管狭窄患者进行治疗可有效改善患者食管狭窄水平,提高其生活质量,同时并发症发生率可控,具有较高的治疗安全性。

Objective:To analyze the effect on endoscopic implantation of esophageal stent in the treatment of patients with malignant esophageal stenosis.Methods:A total of 86 patients with esophageal cancer complicated with esophageal stenosis admitted to our hospital from January 2021 to December 2022 were selected by random sampling in combination with the inclusion criteria and exclusion criteria,and were randomly numbered 1-86.In the study design,43 cases with odd numbers and the other 43 cases with even numbers were included in the control group and observation group,respectively.Patients in the control group were treated with endoscopic bougie dilation,while patients in the observation group were treated with endoscopic implantation of esophageal stent.The diameter of esophageal stenosis,quality of life scale scores and related complications were compared between the two groups.Results:Before surgery,there was no significant difference in the diameter of esophageal stenosis between groups(P>0.05);after surgery,the diameter of esophageal stenosis in both groups increased significantly and that in the observation group was significantly higher than that in the control group(P<0.05).Before surgery,there was no significant difference in the score of esophageal cancer-specific quality of life scale between groups(P>0.05);after surgery,the scores of esophageal cancer-specific quality of life scale were significantly improved in both groups,and the scores of patients in the observation group were significantly higher than those in the control group(P<0.05).The incidence of complications in the observation group(4.65%,2/43)was significantly lower than that in the control group(18.60%,8/43)(P<0.05).Conclusion:Endoscopic implantation of esophageal stent can effectively improve the level of esophageal stenosis and quality of life in patients with malignant esophageal stenosis,while the incidence of complications is controllable,with higher safety.