不同入路方式对人工膝关节置换术患者应激因子表达的影响

Effect of Different Approaches on the Expression of Stress Factors in Patients Undergoing Total Knee Arthroplasty

目的探讨不同入路方式对人工膝关节置换术患者应激因子表达的影响。方法选取79例膝关节置换术患者的临床资料展开回顾性分析,依据手术入路差异分为股内侧肌组(n=41)和传统入路组(n=38)。比较两组手术指标和应激因子。结果与传统入路组比较,股内侧肌组切口长度、住院时间呈下降趋势(P<0.05)。与手术前比较,两组SOD、MDA上升且股内侧肌组显著低于传统入路组(P<0.05)。结论股内侧肌下入路行膝关节置换术可降低患者应激因子表达。

Objective This paper aims to explore the effects of different approaches on the expression of stress factors in patients undergoing total knee arthroplasty.Methods The clinical data of 79 patients with knee replacement were retrospectively analyzed and divided into medial femoral muscle group(n=41)and traditional approach group(n=38)according to the difference of surgical approaches.The operative indexes and stress factors were compared between the two groups.Results Compared with the traditional approach group,the incision length and hospitalization time in the medial femoral muscle group decreased(P<0.05).Compared with before operation,SOD and MDA in the two groups increased,and those in the medial femoral muscle group were significantly lower than those in the traditional approach group(P<0.05).Conclusion The expression of stress factors in patients can be reduced by total knee replacement through the medial submuscular approach.