益生菌改善维持性血液透析患者肠道微炎症状态的临床效果

Clinical Effect of Probiotics on Improving Intestinal Microinflammation in Patients with Maintenance Hemodialysis

目的探讨益生菌对维持性血液透析患者肠道微炎症的治疗效果。方法60例维持性血液透析患者,随机分为实验组(30例)与对照组(30例),实验组患者给予常规方式治疗;对照组患者在常规治疗的基础上给予益生菌治疗,观察两组患者血清IL-6、TNF-α、hs-CRP水平和营养状况。结果对照组患者血清IL-6、TNF-α、hs-CRP水平改善程度明显优于实验组患者;对照组患者的营养状况改善程度明显优于实验组患者(P<0.05)。结论服用益生菌能够有效稳定患者情绪,使患者从新树立战胜病魔的信心,兼顾安全与疗效。

ObjectiveThis paper aims to explore the clinical effect of probiotics on improving intestinal microinflammation in patients with maintenance hemodialysis.MethodsA total of 60 patients with maintenance hemodialysis were randomized into an experimental group(30 cases)and a control group(30 cases),and the patients in the experimental group were given conventional treatment.Patients in the control group were given probiotic therapy on the basis of conventional treatment.Serum IL-6,TNF-α,hs-CRP levels and nutritional status of patients in the two groups were observed.ResultsThe improvement of serum IL-6,TNF-α,hs-CRP levels in patients of the control group was significantly better than those of patients of the experimental group.The improvement degree of nutritional status of patients in the control group was significantly better than that of the experimental group(P<0.05).ConclusionTaking probiotics can effectively stabilize the patients’emotions and restore their confidence in overcoming the disease,with safety and efficacy.