尿毒症血液透析患者检测血清PTH、SF、CRP水平的临床意义

Clinical Significance of Serum PTH,SF and CRP Levels in Uremic Hemodialysis Patients

目的检测尿毒症血液透析患者血清甲状旁腺素(PTH)、铁蛋白(SF)、C反应蛋白(CRP)水平,为临床有效干预提供参考。方法将2012-2014年本院收治的100例尿毒症血液透析患者纳入研究组,另在同一时间段抽选健康志愿者100例作为对照并纳入常规组,测定所有观察对象的血清PTH、SF以及CRP水平,并通过Pearson相关性分析三者之间的相关性。结果研究组血清PTH、SF、CRP水平高于常规组(P<0.05);CRP水平与SF以及PTH水平呈正相关(P<0.05)。结论实施血液透析的尿毒症患者,体内CRP水平、SF水平、CRP水平普遍呈偏高状态,可作为预测患者病情发展的指标。

ObjectiveThis paper aims to detect the levels of serum PTH(parathyroid hormone),SF(ferritin)and CRP(C-reactive protein)in uremic hemodialysis patients,so as to provide reference for clinical effective intervention.Methods100 uremic hemodialysis patients treated in our hospital from 2012 to 2014 were included in the study group,and 100 healthy volunteers were selected at the same time as the control group and included in the routine group.The levels of serum PTH,SF and CRP of all subjects were measured,and the correlation between the three was analyzed by Pearson correlation.ResultsThe levels of serum PTH,SF and CRP in the study group were higher than those in the routine group(P<0.05);CRP level was positively correlated with SF and PTH level(P<0.05).ConclusionThe levels of CRP,SF and CRP in uremic patients undergoing hemodialysis are generally high,which can be used as an index to predict the development of patients’condition.