抗凝治疗对合并心房颤动的老年血液透析患者脑卒中发生的影响

Effect of Anticoagulant Therapy on Stroke in Elderly Hemodialysis Patients with Atrial Fibrillation

目的探析抗凝治疗对合并房颤(AFib)的老年血液透析患者脑卒中发生的影响。方法以52例老年患者为研究对象,按照是否发生AFib,分为AFib组和非AFib组,每组各26例。针对其中非瓣膜病性AFib脑卒中危险的评分≥2的患者又分别分为A组(华法林,n=13)和B组(阿司匹林,n=13)。比较脑卒中、脑出血的发生情况。结果异常情况发生的指标(脑卒中、脑出血):AFib组>非AFib组(P<0.05)。脑卒中几率A组<B组(P<0.05)。结论AFib老年血液透析患者易患缺血性脑卒中和脑出血,抗凝药物华法林能预防脑卒中的发生。

Objective This paper aims to explore the effect of anticoagulant therapy on stroke in elderly hemodialysis patients with atrial fibrillation(AFib).Methods 52 elderly patients were divided into AFib group and non AFib group,with 26 cases in each group.Patients with non valvular heart AFib stroke risk score≥2 were divided into group A(warfarin,n=13)and group B(aspirin,n=13).The incidence of stroke and intracerebral hemorrhage were compared.Results The indexes of abnormal conditions(stroke and intracerebral hemorrhage):AFib group>non AFib group(P<0.05).The probability of stroke in group A<group B(P<0.05).Conclusion Elderly hemodialysis patients with AFib are prone to ischemic stroke and intracerebral hemorrhage.Anticoagulant warfarin can prevent stroke.