甲状腺癌合并肺结节一例报告及文献复习

Thyroid carcinoma complicated with pulmonary nodules:a case report and literature review

甲状腺癌是内分泌系统中最常见的恶性肿瘤,分化型甲状腺癌是最常见的甲状腺恶性肿瘤,经手术及放射性碘治疗等规范治疗后大部分预后良好,仍有约1%~23%的患者会发生远处转移,远处转移以肺部最为常见,合并肺结节的甲状腺癌患者容易发生误诊。本文报道我院[山东第一医科大学第一附属医院(山东省千佛山医院)]收治的1例68岁女性患者,甲状腺癌术后发现多发肺结节,合并颈部淋巴结转移,行多次服碘治疗,甲状腺球蛋白在治疗过程中有所反复,后经肺穿刺,未发现肿瘤细胞。在回顾国内外相关文献的基础上,本文对该类疾病的诊断作进一步探讨,旨在增加对该疾病的重视,减少误诊,从而提高诊治水平。

Thyroid cancer is the most common malignant tumor in the endocrine system,and differentiated thyroid cancer is the most common thyroid malignant tumor.After standard treatment such as surgery and radioiodine therapy,most of the patients have achieved a good prognosis,but about 1%~23%of the patients still have distant metastasis,which is most commonly found in the lungs.Because the thyroid cancer patients complicated with pulmonary nodules are prone to misdiagnosis,in this paper we reported a 68-year-old female patient admitted to our hospital.After thyroid cancer surgery,multiple pulmonary nodules were found with cervical lymph node metastasis.Repeated iodine treatment was performed,and thyroglobulin increased repeatedly during the treatment.After lung puncture,no tumor cells were found.Based on the reviews of relevant literature both at home and abroad,we further studied and discussed the diagnosis of this disease,which is aimed to draw clinicians'attention to this disease,reduce misdiagnosis and improve the level of diagnosis and treatment.