脓毒症休克患者心室-动脉耦联的研究

Research progress of ventricular-arterial coupling in patients with septic shock

脓毒症休克是指严重感染导致的急性心血管失代偿和血流动力学障碍的危重疾病。由于心血管功能依赖心脏和循环之间动态的相互作用,所以对于脓毒症休克的患者,优化心脏和血管之间的匹配关系有助于改善心血管功能。心室-动脉耦联是指心脏功能与外周血管功能相互匹配的关系,通过心室-动脉耦联的评估有助于早期发现潜在的危险患者。本文讨论了脓毒症休克的概念、心室-动脉耦联的机制、脓毒症休克患者心室-动脉耦联的相关因素及评估工具。

Septic shock is a critical disease with acute cardiovascular decompensation and hemodynamic disturbance caused by severe infection.Because cardiovascular function depends on the dynamic interaction between the heart and the circulation,optimizing the matching relationship between the heart and blood vessels helps to improve cardiovascular function in patients with septic shock.Ventricular-arterial coupling refers to the mutually matching relationship between cardiac function and peripheral vascular function,and the evaluation of ventricular-arterial coupling facilitates the early detection of potentially dangerous patients.In this review,we discuss the concept of septic shock,the mechanisms of ventricular-arterial coupling,the factors associated with ventricular-arterial coupling in patients with septic shock,and the assessment tools.