摘要
重症新冠肺炎与一般重症肺炎在临床特征和病理生理机制方面存在明显不同,严重免疫系统损伤和多器官功能受累是其突出的临床特征,呼吸系统损伤只是其病理生理的一个侧面,因此在临床救治中应重视新型冠状病毒感染的特殊性,在强调氧气疗法和呼吸机支持治疗的同时,应突出免疫调节治疗和其他重要器官支持治疗的优先地位,尽早开始应用免疫干预方法和血液净化改善内环境等器官支持措施。这对未来重症新冠肺炎患者的救治有重要指导意义。
Severe COVID-19 is different from the common severe pneumonia in clinical characteristics and pathophysiology.Severe immune system damage and multiple organ involvement are prominent clinical features.Respiratory system damage is only one side of its pathophysiology,which suggests that the specificity of novel coronavirus infection should be emphasized in clinical treatment,and oxygen should not be overemphasized.The priority of immunomodulatory therapy and other important organ support therapy should be emphasized,and the organ support measures such as immune intervention and blood purification should be applied as early as possible.That is of great importance for the treatment of severe COVID-19.
作者
李立艳
李蕾
孟庆义
Li Liyan;Li Lei;Meng Qingyi(Emergencyand infection disease Department,Beijing first integrated traditional chinese and western medicine hospital;Emergency Department,Chinese PLA General Hospital,Beijing,China)
