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低分子肝素疗法用于辅助生殖技术(ART)妊娠后复发性流产治疗的价值及对激素水平的影响 被引量:4

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摘要 目的研究低分子肝素疗法应用于辅助生殖技术(ART)妊娠后复发性流产患者中的价值。方法抽取本院在2017年2月~2020年11月接收的ART妊娠后复发性流产的患者,按照随机分配原则分为对照组(n=45,行常规治疗)和观察组(n=45,行低分子肝泰治疗)。观察比较两组患者的凝血指标、再次妊娠结局、不良反应情况。结果治疗前,两组患者的凝血指标相比较,P>0.05。治疗后,与对照组比较,观察组的D-二聚体(D-D)、纤溶酶原激活物抑制物1(PAI-1)、纤维蛋白原水平对比显著降低(P<0.05)。与对照组相比,观察组活产率显著升高(P<0.05)。两组患者的不良反应情况无明显区别(P>0.05)。结论低分子肝素治疗ART妊娠后复发性流产的患者,能有效改善患者的凝血情况,提高活产率,治疗效果显著。
机构地区 河南省人民医院
出处 《沈阳药科大学学报》 CAS CSCD 北大核心 2021年第S02期23-23,25,共2页 Journal of Shenyang Pharmaceutical University
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