摘要
目的通过整理分析国内外匹莫齐特抗癌机制相关研究,为后续研究提供参考。方法利用中国知网和PubMed等检索平台,检索匹莫齐特在不同肿瘤中的机制研究。结果整理分析文献发现,匹莫齐特对多种癌细胞均具有抑制作用,且抑制作用可能通过多种途径实现。结论系统分析匹莫齐特的抗癌机制,有望为后续研究提供参考。
Objective To provide a reference for subsequent research by collecting and analyzing correlative researches of pimozide.Methods Based on the search platforms such as CNKI and PubMed,the relevant studies of the anti-cancer mechanisms of pimozide were searched.Results We found that pimozide had an inhibitory effect on tumors by analyzing the literatures,and the inhibition effect might be achieved in a variety of ways.Conclusion The systematic review of the anti-cancer mechanism of pimozide will be expected to provide a reference for further research.
作者
刘双萍
周兴智
蒋革
LIU Shuangping;ZHOU Xingzhi;JIANG Ge(Medical College,Dalian University,Dalian 116622,China;School of Life Science and Biotechnology,Dalian University,Dalian 116622,China)
出处
《沈阳药科大学学报》
CAS
CSCD
北大核心
2020年第3期282-288,共7页
Journal of Shenyang Pharmaceutical University
基金
国家自然科学基金资助项目(31560312)
辽宁省自然科学基金指导计划(201602020).
关键词
匹莫齐特
抗癌机制
进展
pimozide
anticancer mechanism
progress