血清TSH水平与甲状腺功能正常冠心病患者并发高尿酸血症的关系分析

The Relationship between Serum Tsh Level and Hyperuricemia in Patients with Coronary Heart Disease with Normal Thyroid Function

目的探讨研究血清促甲状腺激素(TSH)与甲状腺功能正常冠心病患者的关系以及与高尿酸血症的临床关系分析。方法此次研究,选取四川省攀枝花市中心医院接受治疗的90例甲状腺功能正常冠心病患者为冠心病组,患者就诊时间为2017年6月—2019年10月期间,同时选取本院体检结果为健康的90例志愿者为志愿组,后针对冠心病组,根据是否并发高尿血酸症分为研究组(并发高尿血酸症),对照组(未并发高尿血酸症),进一步探讨甲状腺功能正常冠心病患者的血清促甲状腺激素(TSH)情况。结果冠心病组、志愿组两组患者的血清TSH水平、血清T3水平、血清T4水平检测结果,比较差异无统计学意义(P>0.05);年龄≤65岁亚组中,冠心病组患者的血清TSH水平明显高于志愿组,差异有统计学意义(P<0.05);年龄≤65岁亚组中,冠心病组、志愿组两组的血清T3水平、血清T4水平值检测结果比较差异无统计学意义(P>0.05),而年龄>65岁亚组中,冠心病组患者与志愿组两组的血清TSH水平、血清T3水平、血清T4水平,差异无统计学意义(P>0.05);研究组患者的血清TSH水平、甘油三酯水平值相对比,要高于对照组患者,同时患其高密度脂蛋白胆固醇水平值检测结果,要显著低于对照组患者。结论具备明显差那况下,血清促甲状腺激素(TSH)与冠心病发病率呈现正相关,而年龄也是对冠心病合并高尿血酸症造成影响的因素之一,且血清促甲状腺激素(TSH)水平值较高的患者,即使其甲状腺功能正常,出现冠心病患者合并高尿血酸症的可能性也较高。

Objective To investigate the relationship between serum thyrotropin(TSH)and patients with coronary heart disease with normal thyroid function and the clinical relationship between TSH and hyperuricemia.Methods 90 cases of normal thyroid function in patients with coronary heart disease of coronary heart disease group were selected in this study in Panzhihua Central Hospital.The patients clinical time was during June 2017 to October 2019,at the same time,the hospital physical exa mination results of 90 cases of healthy volunteers for volunteer group were choosen.According to whether the high concurrency nixie acid disease is divided into research group(high concurrency nixie acid syndrome),the control group(without concurrent high nixie acid syndrome),normal thyroid function in patients with coronary heart disease serum thyroid stimulating hormone(TSH)was further explored.Results There was no significant difference in serum TSH level,serum T3 level and serum T4 level between the CHD group and the volunteer group.In the subgroup with age≤65 years old,the serum TSH level of patients in the CHD group was significantly higher than that in the volunteer group,with a significant difference(P<0.05).In the age≤65 subgroup,there was no significant difference in the detection results of serum T3 level and serum T4 level between the coronary heart disease group and the volunteer group,while there was no significant difference in serum TSH level,serum T3 level and serum T4 level between the coronary heart disease group and the volunteer group in the age 65 subgroup.The serum TSH level and triglyceride level of patients in the study group were higher than those in the control group,and the detection results of high-density lipoprotein cholesterol level were significantly lower than those in the control group,with a significant difference(P<0.05).Conclusion The research data shows,thyroid function normal age acuities were 65 cases of coronary heart disease patients,serum thyroid stimulating hormone(TSH)positively related with the incidence of coronary heart disease,and age is also affect coronary heart disease and high nixie acid disorder and one of the factors and serum thyroid stimulating hormone(TSH)patients with high level,even if its normal thyroid function,the possibility of coronary heart disease(CHD)patients and high nixie acid disorder is higher.