磁共振成像对非小细胞肺癌的诊断价值分析

Diagnostic value of Magnetic Resonance Imaging for the Non-Small Cell Lung Cancer

目的:探讨磁共振成像(Magnetic resonance imaging,MRI)对非小细胞肺癌的诊断价值。方法:选择2016年9月-2019年4月南京医科大学附属脑科医院(胸科院区)放射科收治的肺部结节患者74例,包括病理证实为肺部良性病变54例(良性组)和非小细胞肺癌20例(肺癌组)。所有患者都给予常规MRI、增强MRI与磁共振扩散加权成像(Diffusion weighted imaging,DWI),记录影像学特征并评估其诊断价值。结果:肺癌组的病灶形态、边缘等MRI特征与良性组对比差异无统计学意义(P>0.05)。在b值=0、600、800、1000 s/mm^2条件下,肺癌组的病灶表观扩散系数(Apparent diffusion coefficient,ADC)值都显著低于良性组(P<0.05)。肺癌组的病灶MRI增强Ⅰ型+Ⅱ型比例显著高于良性组(P<0.05)。MRI鉴别诊断非小细胞肺癌的敏感性与特异性为98.1%和94.4%。结论:MRI用于非小细胞肺癌的诊断能反映病灶组织的血流动力学与水分子活动状况,具有较高的诊断敏感性与特异性。

Objective:To investigate the diagnostic value of magnetic resonance imaging(MRI)on non-small cell lung cancer.Methods:From September 2016 to April 2019,74 patients with pulmonary nodules admitted to the affiliated brain hospital of Nanjing medical university were selected and pathologically confirmed including 54 patients of benign lung lesions(benign group)and 20 patients of non-small cell lung cancer(lung cancer group).All patients were given conventional MRI,enhanced MRI and diffusion weighted imaging(DWI),recorded the imaging features and evaluate its diagnostic value.Results:There were no significant differences in the MRI features of the lesions and margins compared between the lung cancer group and the benign group(P>0.05).Under the condition of b value=0,600,800,1000 s/mm2,the apparent diffusion coefficient(ADC)of the lung cancer group were significantly lower than that of the benign group(P<0.05).The MRI enhanced type I+II ratios of the lung cancer group were significantly higher than that of the benign group(P<0.05).The sensitivity and specificity of MRI for the differential diagnosis of non-small cell lung cancer were 98.1%and 94.4%.Conclusion:The application of MRI in the diagnosis of non-small cell lung cancer can reflect the hemodynamics and water molecule activity of the lesion tissue,and has higher diagnostic sensitivity and specificity.