银杏达莫注射液、多奈哌齐治疗轻度血管性认知障碍的临床研究

Clinical study of Ginkgo biloba injection and donepezil in the treatment of mild vascular cognitive impairment

目的:探究银杏达莫注射液、多奈哌齐治疗轻度血管性认知障碍。方法:将2019年1月-2019年12月我院收治的80例轻度血管性认知障碍患者均分为两组,每组患者40例。对照组患者用药多奈哌齐,观察组患者为联合用药银杏达莫注射液。对比两组患者的MoCA各项评分以及总评分。结果:对比两组患者的治疗有效率,观察组患者治疗总有效率显著优于对照组患者(p=0.044),观察组患者MoCA各项评分以及总评分均显著优于对照组患者(p<0.05)。结论:银杏达莫注射液、多奈哌齐联合用药能够有效的改善MVCI患者的记忆力,延缓病症的进展,效果突出。

Objective:To explore the effect of intravenous ginkgo-damole on mild vascular cognitive impairment(MVCI).Methods:Eighty patients with vascular cognitive impairment in our hospital from January 2019 to December 2019 were divided into control group and combination therapy group,40 cases in each group.The control group was treated with donepezil,and the combination therapy group was treated with donepezil and intravenous ginkgo-damole.MOCA scores and total scores of the two groups were compared.Results:Compared with the treatment efficiency of the two groups,the total effective rate of the observation group was significantly better than that of the control group(P=0.044),and the MOCA scores and total scores of the observation group were significantly better than those of the control group(P<0.05).Conclusion:The concomitant use of intravenous ginkgo-damole with donepezil can improve the outcome of patients with MVCI.