2014-2016年重庆市九龙坡区新发恶性肿瘤生存分析

Survival of patients newly diagnosed with malignant tumor in Jiulongpo District of Chongqing City from 2014 to 2016

目的分析2014-2016年重庆市九龙坡区居民新发恶性肿瘤患者的生存情况,为恶性肿瘤防治提供参考依据。方法收集中国肿瘤登记平台2014-01-01-2016-12-31户籍为九龙坡区的新发恶性肿瘤资料,通过主动随访和与死因数据比对获得随访资料,随访截止日期为2020-12-31。采用寿命表法计算5年观察生存率(OSR)和中位生存时间,不同性别、年龄组间生存率比较采用Log-rankχ^(2)分析。结果2014-2016年九龙坡区新发恶性肿瘤病例合计7095例,平均粗发病率为262.38/10万,中标率为193.49/10万,5年观察生存率为38.99%,中位生存时间0.82年;发病前10位恶性肿瘤中,5年观察生存率最高是乳腺癌(76.87%),最低为胰腺癌(14.51%)。不同性别间比较,总恶性肿瘤及肺癌5年观察生存率差异均有统计学意义(χ^(2)_(总)=261.67,P<0.05;χ^(2)_(肺癌)=19.82,P<0.05),不同年龄组比较,总恶性肿瘤、食管癌及卵巢癌5年观察生存率差异有统计学意义(均P<0.05),全部恶性肿瘤5年观察生存率随着年龄增加而下降,差异有统计学意义,χ^(2)_(趋势)=30.93,P<0.05。结论2014-2016年九龙坡区恶性肿瘤5年观察生存率随年龄增加而下降,胰腺癌、肺癌、肝癌患者生存状况较差,乳腺癌、宫颈癌预后相对较好。

Objective To analyze the survival of malignant tumor patients with newly diagnosed in Jiulongpo District of Chongqing City from 2014 to 2016,and provide reference for the prevention and treatment of malignant tumor.Methods The data of malignant cancers patients with newly diagnosed and registered in Jiulongpo District from China Cancer Registry during January 1,2014 to December 31,2016 were collected,and follow-up data through active follow-up and comparison with cause of death data were obtained in the study,and followed-up till December 2020.Five-year observed survival rate and median survival time were calculated by the Life table method.Log-rank test was used for comparing the survival rates of patients among different gender and age.Results Totally 7095 cases of malignant tumor patients were registered in Jiulongpo District from 2014 to 2016,and average crude incidence rate was 262.38/10^(5),and standardized cidence rate was 193.49/10^(5),and five-year observed survival rate was 38.99%,and median survival time was 0.82 years.Among the top 10 malignant tumors patients,breast cancer had the highest five-year observed survival rate of 76.87%,and pancreatic cancer had the lowest five-year observed survival rate of 14.51%.The overall five-year observed survival rate of malignant tumor and the five-year observed survival rate of lung cancer in males were significantly lower than those in females(χ^(2)_(overall)=261.67,P<0.05;χ^(2)_(lung cancer)=19.82,P<0.05).The five-year observed survival rate of all malignant cancer and esophageal cancer and ovarian cancer in different age groups were significant differences(P<0.05).The overall five-year observed survival rate of all malignant tumors were decreased with the increasing age(χ^(2)_(trend)=30.93,P<0.05).Conclusions The five-year observed survival rate of the malignant tumor patients in Jiulongpo District of Chongqing City during 2014-2016 decreased with the increase of age,the prognosis of pancreatic cancer,lung cancer and liver cancer patients was worse,and that of female breast cancer and cervical cancer patients was relatively better.