基于logistic回归方程对儿童疱疹性咽颊炎相关影响因素分析

Analysis of influencing factors of pediatric herpetic pharyngitis based on logistic regression equation

目的探讨儿童疱疹性咽颊炎(HA)的相关影响因素,并制定针对性护理干预策略,为预防控制该病提供科学依据。方法选取2021-02-10-2022-03-24平顶山市第一人民医院收治的459例HA患儿作为研究对象,采用1∶1原则纳入同院同期健康体检儿童459名作为对照组。对比2组的临床资料,logistic回归方程分析参与HA发生的影响因素。结果单因素分析结果显示,2组不同年龄、卫生习惯、免疫功能、营养障碍、C反应蛋白(CRP)水平、血清淀粉样蛋白A(SAA)水平比较,差异有统计学意义,均P<0.05。多因素logistic回归分析结果显示,年龄≤1岁(OR=2.351,95%CI为1.113~4.965,P=0.006)、卫生习惯较差(OR=2.873,95%CI为1.468~5.624,P=0.010)、免疫功能异常(OR=5.157,95%CI为2.357~11.285,P<0.001)、合并营养障碍(OR=2.313,95%CI为1.236~4.327,P=0.005)、CRP水平≥3.34 mg/L(OR=3.487,95%CI为2.113~5.753,P<0.001)、SAA水平≥6.53 mg/L(OR=3.660,95%CI为2.134~6.278,P<0.001)是儿童发生HA的危险因素。结论儿童HA发生受多种因素影响,主要与年龄、卫生习惯、免疫功能、营养障碍及CRP、SAA水平等有关。临床上应着重关注具有上述因素个体,针对性制定预防措施,以避免其发生,促进儿童身心健康发展。

Objective To explore the related factors of children with herpesopharyngeal buccinitis(HA),and to formulate targeted nursing intervention strategies to provide scientific basis for the prevention and control of the disease.Methods A total of 459 children with HA admitted to the First People’s Hospital of Pingdingshan City from February 10,2021 to March 24,2022 were selected as subjects,and 459 healthy children in the same hospital during physical examination were included in a ratio of 1∶1 as the control group.The clinical data of the two groups were compared,and the influencing factors involved in the occurrence of HA were analyzed by logistic regression equation.Results Univariate analysis showed that there were statistically significant differences in age,health habits,immune function,nutritional disorders,C-reactive protein(CRP)level and serum amyloid protein A(SAA)level between the two groups(P<0.05).The results of multivariate logistic regression analysis showed that age≤1 year old(OR=2.351,95%CI:1.113-4.965,P=0.006),poor hygiene habits(OR=2.873,95%CI:1.468-5.624,P=0.010),abnormal immune function(OR=5.157,95%CI:2.357-11.285,P<0.001),combination with nutritional disorders(OR=2.313,95%CI:1.236-4.327,P=0.005),CRP level≥3.34 mg/L(OR=3.487,95%CI:2.113-5.753,P<0.001),SAA level≥6.53 mg/L(OR=3.660,95%CI:2.134-6.278,P<0.001)were risk factors for HA in children.Conclusions The occurrence of HA in children is affected by many factors,which are mainly related to age,health habits,immune function,nutritional disorders,CRP and SAA levels,etc.Clinical medical staff should pay attention to individuals with the above factors and formulate preventive measures to avoid its occurrence and promote the healthy development of physical and mental health of children.