2016-2020年锦州市性病门诊男性就诊者艾滋病哨点监测结果分析

Analysis of sentinel surveillance results of male outpatients with sexually transmitted disease in Jinzhou from 2016 to 2020

目的了解锦州市性病门诊男性就诊者中,艾滋病病毒(HIV)、梅毒和丙肝病毒(HCV)感染水平及其危险因素。方法对锦州市2016-2020年艾滋病哨点医院性病门诊男性就诊者进行问卷调查,并抽取血样检测HIV、HCV和梅毒抗体。不同年份分类变量组间差异比较采用χ^(2)检验,HIV抗体阳性影响因素采用多因素Logistic回归模型。结果2016-2020年共检测2000例性病门诊男性就诊者,HIV抗体、梅毒抗体、HCV抗体阳性率分别为1.00%、31.00%和0.45%;2016-2020年各年度HIV抗体阳性率差异有统计学意义,χ^(2)=9.596,P=0.048;梅毒抗体阳性率差异有统计学意义,χ^(2)=56.241,P<0.001;HCV抗体阳性率差异无统计学意义,χ^(2)=8.259,P=0.083。2016-2020年艾滋病知识知晓率平均为82.40%,2016-2020年各年度差异无统计学意义,χ^(2)=3.365,P=0.499。多因素分析结果表明,与同伴发生肛交性行为(OR=31.459,95%CI为7.325~135.107,P<0.001)和梅毒抗体阳性(OR=3.689,95%CI为1.437~9.467,P=0.007)是HIV感染的主要危险因素。结论性病门诊男性就诊者是艾滋病防治重点关注人群,应加强对该人群艾滋病宣传教育和行为干预,提高其艾滋病知识知晓率。与同伴发生肛交性行为和梅毒抗体阳性是HIV感染的主要危险因素。探索行而有效的干预机制与方式,减少性传播疾病的蔓延。

Objective To understand the rate of human immunodeficiency virus(HIV),syphilis and Hepatitis C virus(HCV)infection and associated influence factors among male sexually transmitted disease(STD)clinic outpatients in Jinzhou City of Liaoning Province.Methods A questionnaire survey was conducted among male outpatients in STD clinic in Jinzhou from 2016 to 2020.Blood samples were collected to test HIV,syphilis and HCV.Theχ^(2)test was applied for the comparison between classification variables in different years.Logistic regression model was used to analyze the associated factors of HIV.Results A total of 2000 male STD clinic outpatients were tested from 2016 to 2020.The rate of HIV infection among 2000 outpatients was 1.00%,the rate of syphilis infection was 31.00%,the rate of HCV infection was 0.45%.The difference in the positive rate of HIV antibodies between 2016 and 2020 was statistically significant(χ^(2)=9.596,P=0.048).The difference in the positive rate of syphilis antibodies was statistically significant(χ^(2)=56.241,P<0.001).The difference in the positive rate of HCV antibodies was not statistically significant(χ^(2)=3.365,P=0.499).The average awareness rate of AIDS knowledge from 2016 to 2020 was 82.40%,and the difference between 2016 and 2020 was not statistically significant(χ^(2)=3.365,P=0.499).Multivariate Logistic regression analysis showed that having homosexual anal sex(OR=31.459,95%CI was 7.325-135.107,P<0.001)and syphilis infection(OR=3.689,95%CI was 1.437-9.467,P=0.007)were the high risk factors for HIV infection.Conclusion Male patients in STD clinics are the focus groups for AIDS prevention and treatment.AIDS publicity and education and behavior intervention should be strengthened to increase their awareness of AIDS knowledge.Anal sex with a partner and positive syphilis antibodies are the main risk factors for HIV infection.Explore effective intervention mechanisms and methods to reduce the spread of sexually transmitted diseases.