蒙药绿松石的质量标准研究

Study on the Quality Standard of Mongolian Medicine Turquoise

目的建立蒙药绿松石的质量标准。方法收集不同产地绿松石,共10批。观察绿松石样品和粉末的性状并进行理化鉴别;按2020年版《中国药典》(四部)通则方法测定绿松石样品中水分、浸出物含量;采用原子吸收光谱法测定绿松石样品铜元素含量。结果绿松石为不规则、周围带有黑石的块状物,表面蓝绿色,体重,质硬脆,难砸碎,断面呈贝壳状,蜡样光泽,粉末呈灰绿色,无臭,味淡;理化鉴别结果显示,呈铜盐反应;10批次样品中水分含量为0.41%-3.94%(SD=1.37%),浸出物含量为0.21%-0.81%(SD=0.21%),铜元素含量为3.03%-4.63%(SD=0.63%)。结论初步拟定绿松石中水分含量不得超多5.0%、浸出物含量不得低于0.10%,铜元素含量应为2.60%-4.84%,制定的标准可用于蒙药材绿松石的质量控制。

Objective To establish the quality standard of Mongolian Medicine Turquoise.Method Totally 10 batches of Turquoise were collected from different localities.The characteristics of Turquoise samples were observed and Identified.The contents of water,extract in turquoise were determined according to the method stated in 2020 edition of Chinese Pharmacopeia(partⅣ).The contents of copper in Turquoise were determined by AAS.Result Turquoise is an irregular lump with black stones around it and blue-green on the surface,hard and brittle in texture,with shell like cross section and wax like luster.The powder is grayish green,odorless and mild in taste;The results of physical and chemical identification showed that it was copper salt reaction;In the 10 batch of samples,the contents of water were 0.41%-3.94%(SD=1.37%);the contents of extract were 0.21%-0.81%(SD=0.21%);the contents of copper were 3.03%-4.63%(SD=0.63%).CONCLUSIONS It is preliminarily proposed that the content of water in Turquoise is not more than 5.0%;the content extract is not less than 0.10%;the content of copper should be in the range of 2.60%-4.84%;Established standard can be used for the quality control of Turquoise.