揿针联合中医五行音乐改善晚期肿瘤相关抑郁状态随机对照临床研究

Effectiveness of Thumbtack Needle with Traditional Chinese Medicine Five Elements Music in Relieving Cancer Related Depression: a Randomized Controlled Trial

目的观察揿针联合中医五行音乐改善晚期肿瘤相关抑郁状态临床疗效。方法针对肝郁气滞型抑郁,将综合焦虑/抑郁情绪测定表评分大于7分且小于15分的70例肿瘤患者,按照1:1比例随机分配到干预组(35例)和对照组(35例),干预组采用揿针联合中医五行音乐干预,对照组单纯聆听中医五行音乐,为期4周,观察治疗前后综合医院焦虑/抑郁(HADS)情绪测定表评分变化。结果各组组内比较,无论试验组还是对照组,治疗前后各组组内不同疗程HADA中的抑郁水平差异有统计学意义(P<0.05);两组组间比较,试验组对HADA中的焦虑变化差异有统计学意义(P<0.05)。结论揿针联合中医五行音乐疗法能够很好的改善晚期肿瘤患者的抑郁状态,为中医各型抑郁非药物干预研究奠定基础。

Objective To observe the curative effect of thumbtack needle combined with Traditional Chinese Medicine(TCM)Five elements music in relieving cancer related depression.Method In this study,we selected patients who met the inclusion criteria diagnosed by the qi stagnation of liver.According to the principle of randomization,the 70 patients were randomly divided into control group and intervention group.The intervention group(35 individuals treated with Thumbtack needle with TCM five elements music,and control group(30 individuals who were treated with TCM five elements music,),to measure the General Hospital Anxiety/Depression scale(HADS).Results there were significantly differences for the depression scales of HADS when comparing pro-post treatment in each group respectively(P<0.05).There were significantly differences for the anxiety of HADS after treatment,when comparing with two groups(P<0.05).Conclusion TCM five elements music was shown being the unique advantages in relieving cancer related depression,the thumbtack needle therapy combined with TCM five elements music could be used as a traditional Chinese medicine(TCM)non-dmg therapy to improve cancer related depression.