八段锦对糖尿病患者糖脂代谢干预效果的Meta分析

Meta-analysis of Intervention Effect of Baduanjin on Glucose and Lipid Metabolism in Diabetic Patients

目的系统评价八段锦对糖尿病患者糖脂代谢水平的影响。方法系统检索国内外数据库,纳入有关八段锦治疗糖尿病的随机对照试验进行荟萃分析。结果本研究共纳入16项研究,包括1185例糖尿病患者,其中试验组共591例,对照组共594例。Meta分析结果显示:(1)糖代谢方面:疗程不足6个月时,八段锦组糖尿病患者的FPG(MD=-0.60,95%CI[-0.98,-0.23])、HbA1c(MD=-0.8,95%CI[-0.99,-0.61])改善情况优于对照组;疗程达6个月时,八段锦组糖尿病患者的FPG(MD=-1.07,95%CI[-1.67,-0.47])、P2hPG(MD=-1.2,95%CI[-2.31,-0.08])、HbA1c(MD=-0.73,95%CI[-1.14,-0.32])改善程度优于对照组。(2)脂代谢方面:疗程不足6个月时,八段锦组糖尿病患者的TC(MD=-0.79,95%CI[-1.13,-0.45])、HDL(MD=0.21,95%CI[0.12,0.29])改善情况优于对照组;疗程达6个月时,八段锦组糖尿病患者的TC(MD=-0.46,95%CI[-0.71,-0.20])、TG(MD=-0.60,95%CI[-1.14,-0.06])、HDL(MD=0.21,95%CI[0.09,0.33])改善情况优于对照组。结论作为辅助治疗手段,八段锦具有进一步改善糖尿病患者糖脂代谢水平的作用,尤其在FPG、HbA1c、TC、HDL方面的疗效较为稳定,同时安全性较好,具有良好的推广应用价值。

Objective:To evaluate the effect of Baduanjin on glucose and lipid metabolism in diabetic patients.Methods:The domestic and foreign databases were systematically searched,and the randomized controlled trials of Baduanjin in the treatment of diabetes were included for meta-analysis.Results:A total of 16 studies were included in this study,including 1185 diabetic patients,591 in the experimental group and 594 in the control group.Meta-analysis results show:(1)Glucose metabolism:when the treatment course is less than 6 months,the improvement of FPG(MD=-0.60,95%CI[-0.98,-0.23]),HbA1c(MD=-0.8,95%CI[-0.99,-0.61])in Baduanjin group is better than that in the control group;After 6 months of treatment,the improvement of FPG(MD=-1.07,95%CI[-1.67,-0.47]),P2hPG(MD=-1.2,95%CI[-2.31,-0.08]),HbA1c(MD=-0.73,95%CI[-1.14,-0.32])and HbA1c(MD=-0.73,95%CI[-0.32])in Baduanjin group are better than those in the control group.(2)Lipid metabolism:when the course of treatment is less than 6 months,the improvement of TC(MD=-0.79,95%CI[-1.13,-0.45]),HDL(MD=0.21,95%CI[0.12,0.29])in Baduanjin group is better than that in the control group;After 6 months of treatment,the improvement of TC(MD=-0.46,95%CI[-0.71,-0.20]),TG(MD=-0.60,95%CI[-1.14,-0.06]),HDL(MD=0.21,95%CI[0.09,0.33])in Baduanjin group is better than that in the control group.Conclusion:As an adjuvant therapy,Baduanjin has the effect of further improving glucose and lipid metabolism level of diabetic patients,especially in FPG,HbA1c,TC,HDL,with stable curative effect,good safety and good popularization and application value.