原发性肝癌切除术后精准序贯介入治疗的临床效果分析

Clinical Analysis of Precise Sequential Interventional Therapy after Resection of Primary Liver Cancer

目的研究与分析原发性肝癌切除术后精准序贯介入治疗的临床效果。方法选取该院2017年11月—2019年5月进行原发性肝癌切除术治疗的患者88例,随后根据患者的治疗方式进行分组,主要分为常规序贯组以及精准序贯组,各44例。对常规序贯组患者采取常规序贯介入治疗,而对精准序贯组患者采取精准序贯介入治疗,随后观察两组患者的甲胎蛋白水平、谷丙转氨酶水平、血清白蛋白水平、Child—Pugh评分、肿瘤复发率以及生存率等指标。结果精准序贯组与常规序贯组的甲胎蛋白水平、谷丙转氨酶水平、血清白蛋白水平、Child—Pugh评分、术后3年肿瘤复发率以及生存率等指标均较佳,但是精准序贯组患者的各项指标更佳[(117.31±330.77)g/mL,(164.66±83.71)U/L,(34.95±3.54)g/L,(8.82±2.98)g/L,27.3%,79.5%]vs[(153.66±255.74)g/mL,(187.25±230.11)U/L,(33.05±2.58)g/L,9.85±3.11g/L,47.7%,61.4%],差异有统计学意义(t/χ~2=2.336、3.965、4.021、6.515、4.020、3.024,P<0.05)。结论原发性肝癌切除术后精准序贯介入治疗的临床效果显著,值得推广。

Objective To study and analyze the clinical effects of precise sequential interventional therapy after resection of primary liver cancer.Methods Eighty-eight patients with primary liver cancer resection were performed from November 2017 to May 2019 in the hospital.Then,according to the treatment methods of patients,they were divided into regular sequential group and precise sequential group.There were 44 cases in each group.Conventional sequential intervention was performed in patients in the conventional sequen-tial group,and precise sequential intervention was performed in patients in the precise sequential group.The alpha-fetoprotein level,alanine aminotransferase level,serum albumin level,Child-Pugh scores,tumor recurrence rates,and survival rates.Results The al-pha-fetoprotein level,alanine aminotransferase level,serum albumin level,Child-Pugh score,3 years after operation tumor recurrence rate,and survival rate were better in the precise sequential group and the conventional sequential group,but the patients in the pre-cise sequential group were better.The indicators were better[(117.31±330.77)g/mL,(164.66±83.71)U/L,(34.95±3.54)g/L,(8.82±2.98)g/L,27.3%,79.5%vs(153.66±255.74)g/mL,(187.25±230.11)U/L,(33.05±2.58)g/L,(9.85±3.11)g/L,47.7%,61.4%],and the difference was statistically significant(t/χ~2=2.336,3.965,4.021,6.515,4.020,3.024,P<0.05).Conclusion The clinical effect of precise sequential interventional therapy after resection of primary liver cancer is significant and worthy of promotion.