摘要
为应对临床研究评价指标存在的不规范、不一致、不重要等问题,方法学专家提出了核心指标集(COS)的概念。有效性试验核心结局指标(COMET)工作组的成立,促进了COS的国际化推广和应用。从COS的概念及作用、COS研究平台、COS研制方法、中医药临床研究核心指标集(COS-TCM)等四个方面进行阐述,为核心指标集研究提供参考。
To deal with the nonstandard,inconsistent and unimportant clinical research evaluation indicators,methodologists put forward the concept of core outcome set(COS).The establishment of core outcome measures in effectiveness trials(COMET)working group has facilitated the international promotion and application of COS.This paper expounds the concept and function of COS,COS research platforms,COS development methods,and the core outcome set of traditional Chinese medicine(COS-TCM)for clinical trials,thereby providing references for the research of core outcome set.
作者
强晓钰
季昭臣
生晓迪
刘春香
王辉
庞博
张俊华
QIANG Xiaoyu;JI Zhaochen;SHENG Xiaodi;LIU Chunxiang;WANG Hui;PANG Bo;ZHANG Junhua(Evidence⁃Based Medicine Center,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China)
出处
《上海中医药杂志》
2022年第8期113-117,共5页
Shanghai Journal of Traditional Chinese Medicine
基金
国家自然科学基金项目(82074583)
关键词
核心指标集
评价指标
方法学
中医药学
循证医学
临床试验
core outcome set
evaluation indicator
methodology
traditional Chinese medicine
evidence-based medicine
clinical trial