摘要
基于伏邪理论探讨肠-肾轴对慢性肾脏病的影响。慢性肾脏病的发病具有隐匿性,与中医伏邪有相似之处;肠道菌群紊乱产生的内毒素及微炎症对肾脏的损伤与伏邪致病具有类似之处;当肠黏膜发生免疫炎症时会导致慢性肾脏病的加重,这与伏邪的外发与化火类似。
To explore the effect of intestinal-kidney axis on chronic kidney disease based on the theory of hidden pathogen.The onset of chronic kidney disease was occult,which was similar to the hidden pathogen in traditional Chinese medicine.The damage of kidney caused by endotoxin and microinflammation on account of intestinal flora disturbance was similar to that caused by hidden pathogens.When the immune inflammation of intestinal mucosa occurred,it could lead to the aggravation of chronic kidney disease,which was similar to the external occurrence of hidden pathogen and hidden pathogen transforming into fire.
作者
徐飞鹏
张亚君
沈沛成
姚东升
吴卿
XU Feipeng;ZHANG Yajun;SHEN Peicheng;YAO Dongsheng;WU Qing(Department of nephrology,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;General Practitioner,Shanghai Minhang Meilong Community Health Center,Shanghai 201101,China;Traditional Chinese Medicine Institute of Kidney Disease,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Key Laboratory of Liver and Kidney Diseases,Ministry of Education,Shanghai 201203,China;Shanghai Key Laboratory of Traditional Chinese Clinical Medicine,Shanghai 201203,China)
出处
《上海中医药杂志》
2022年第5期36-38,共3页
Shanghai Journal of Traditional Chinese Medicine
基金
国家自然科学基金青年基金项目(81904124,81704015)
上海市科委科研计划项目(18401903300)
关键词
伏邪
肠-肾轴
肠道菌群
慢性肾脏病
hidden pathogen
intestine-kidney axis
intestinal flora
chronic kidney disease
