基于Ordinal Logistic回归探讨儿童肺炎支原体肺炎的预后影响因素

Study on the prognostic impact factors of mycoplasmal pneumoniae pneumonia based on Ordinal Logistic regression analysis

目的探讨儿童肺炎支原体肺炎(MPP)的预后相关影响因素。方法回顾性分析2017年1月至2017年12月在上海中医药大学附属龙华医院中医儿科病房住院并接受治疗的250例MPP患儿的临床资料,评价所有患儿的临床疗效,采用Ordinal Logistic回归分析探讨影响MPP预后的因素。结果250例MPP患儿经治疗后,痊愈195例(78.0%)、显效43例(17.2%)、有效12例(4.8%)、无效0例(0%)。Ordinal Logistic回归分析结果表明,中西医结合配合外治和住院前使用中药均有利于MPP的预后,C反应蛋白(CRP)异常、血小板(PLT)计数升高和合并其他病原体则是影响MPP预后的危险因素。结论中西医结合配合外治及早期中药干预均有利于MPP患儿的预后,而合并其他病原体、CRP异常及PLT水平升高则提示MPP患儿预后较差。

Objective To investigate the related prognostic impact factors of children’s mycoplasmal pneumoniae pneumonia(MPP).Methods The clinical data of 250 children with MPP who were hospitalized and treated in the pediatric ward of traditional Chinese medicine in Longhua Hospital Affiliated to Shanghai university of traditional Chinese medicine from January 2017 to December 2017 were retrospectively analyzed.The clinical efficacy of all the children was evaluated,and the prognostic impact factors of MPP were discussed by Ordinal Logistic regression analysis.Results There were 195 cured cases(78.0%),43 markedly effective cases(17.2%),12 effective cases(4.8%)and 0 ineffective case(0%)in 250 children with MPP after treatment.The results of Ordinal Logistic regression analysis showed that,the integrated traditional Chinese and western medicine combined with external treatment and the use of traditional Chinese medicine before admission were helpful to the prognosis of MPP,and the abnormity of C reactive protein(CRP),the increase of platelet(PLT)level and the combination of other pathogens were the risk factors affecting the prognosis of MPP.Conclusion The integrated traditional Chinese and western medicine combined with external treatment and early traditional Chinese medicine intervention is conducive to the prognosis of children with MPP,while the combination of other pathogens,the abnormity of CRP and the increase of PLT level suggest that the prognosis of the children with MPP is poor.