摘要
本文分析了10例正常人和88例上消化道疾病患者胃粘液-碳酸氢盐屏障功能,证实其在正常情况下有中和胃酸、减弱胃蛋白酶活性的作用。球溃患者中和指数和粘液保护指数明显低于正常,可能是伴发胃部病变的一个原因,胃部疾病患者HCO3-和酸性粘蛋白减少是病变损伤上皮细胞的继发结果,胃溃患者中性粘蛋白升高可能与胆汁返流加速可见性粘液分解有关,某些药物对HCO3-分泌可能有促进作用。
Secretion of gastric mucus and bicarbonate was evaluated in 98 subjects including healthy controls and patients with upper gastrointestinal disorders.The neutralizing index and the mucoprotective index in duodenum ulcer were lower,HCO3-and acid mucoprotein in chronic gastric disorders were reduced,and the neutral mucoprotein in gastric ulcer was increased.We conclude that the changes of the composition of gastric mucus and the amount of HCO3-are the causes of gastric complication in duodenum ulcer or secondary epithelial injury of gastric disorders.
出处
《上海医学》
CAS
1988年第10期578-580,共3页
Shanghai Medical Journal
