冠心病患者侧支循环与冠状动脉病变及左心室功能的关系

COLLATERAL CIRCULATION IN PATIENTS WITH CORONARY ARTERY DISEASE

为了测定侧支循环与冠状动脉病变及左心室功能的关系,对66例心绞痛或心肌梗塞患者,行冠状动脉和左心室造影。侧支循环发生率在冠状动脉完全阻塞和多支冠状动脉病变患者明显增高。冠状动脉完全阻塞伴侧支循环形成患者的左心室射血分数和局部室壁运动明显高于冠状动脉完全阻塞无侧支形成患者。本文提示侧支循环形成与冠状动脉病变的阻塞程度及慢性心肌缺血有关。其对冠状动脉阻塞远端区的供血可保护心肌收缩功能。

To determine the relationship between the extent of collateral circulation and the severity of coronary artery disease,and the effects of collaterals on left ventricular(Ⅳ)function,66 patients with angina or myocardial infarction underwent left ventriculography and coronary arteriography.Collateral circulation was more prevalent in patients with total occlusion of coronary arteries or multivessel disease.After myocardial infarction,patients with collateral vessel supplying to infarct region had higher LV ejection fraction and lower abnormal LV wall motion score than those without.The study suggests that in patients with coronary artery disease the extent of collateral circulation may be related to the severity of coronary disease,and collaterai vessels may exert a beneficial effect on LV function by providing retrograde blood flow.