肝性脑病脑电图分析

ELECTROENCEPHALOGRAM CHANGES IN PATIENTS WITH HEPATIC ENCEPHALOPATHY: A REPORT OF 18 CASES

本文报道18例肝性脑病[1例慢性活动性肝炎(CAH),17例重型CAH],脑电图(EEG)检查和动态观察结果,17例EEG有不同程度改变。主要表现呈弥漫性慢活动变化和少数三相波出现,未见局灶变化及痫样放电。18例中属轻度慢活动变化4例,中度者9例,重度者4例,其中4例在中度及重度慢活动变同时伴有三相波。通过EEG随访,发现EEG异常改变与临床演变大致平行,与血氨水平无明显相关,提示EEG对肝性脑病的诊断、疗效观察及预后有一定价值。

This paper reports 18 patients with hepatic encephalopathy.Among them one case was of chronic active hepatitis(CAH)and 17 of severe CAH.They were examined and observed by electroencephalogram(EEG)during the course of the disease.Seventeen out of the 18 cases showed various degrees of changes,the diffuse slow activity and occasional appearance of sporadic triphasic waves.However,no local changes in the specific area of cerebral cortex and epileptic form discharges were observed.In the 18 cases,there were mild changes of EEG findings in 4,moderate in 9,severe in 4 and normal in one.However,sporadic triphasic waves appeared in one moderate case and in 3 severe cases.By serial EEG observations,it was found that the abnormalities of EEG were on the whole parallel to clinical changes.Thus.,EEG changes are valuable in the diagnosis,and observing therapeutic effect of hepatic encephalopathy.