IgA肾病62例的临床和病理

CLINICOPATHOLOGIG CORRELATION IN 62 CASES WITH IgA NEPHROPATHY

IgA肾病(IgAGN)62例,占同期原发性肾小球肾炎(PGN)的20.8%。肾病理损害程度分为Ⅰ~Ⅲ级。呈Ⅲ级损害者92.3%为弥漫系膜增生性。临床表现为反复发作性肉眼血尿者占33.9%。此类患者感染诱因常见,易伴有血清IgA增高。表现为肾病综合征(NS)者占17.7%。较常伴高血压和肾功能减退、肾病理呈Ⅲ级损害者占46.2%。

The clinicopathologic findings in 62 cases with IgA nephropathy were rcviewed.They accounted for 20.3%of the cases with idiopathic glomcrulonephritis(GN)and 69.4%,diffuse mesangial proliferative GN were observed in glomerular lesions.The degree of histopathological dmage was divided into three grades.92.3%cases with gradeⅢpathological damage belonged to diffuse mesengial proliferative GN.The common renal manifestations(?)vere recurrent macroscopic hematuria(RMH)(33.9%),glomerulonepnritis syndrome(22.4%)and nephrotic syndrome(NS)(17.7%).The elevated serum IgA value and infections of upper respiratory tract were frequently encountered in RMH.However,the hypertension,renal functional impairement and gradeⅢpathological damage were more common in NS,