血液透析患者唾液与血液中尿素氮及肌酐浓度的相关比较

THE CORRELATION BETWEEN UREA NITROGEN AND CREATININE CONCENTRATIONS IN SALIVA AND PLASMA OF PATIENTS ON CHRONIC HEMODIALYSIS

作者对17例慢性规律性血液透析患者进行了唾液和血液中尿素氮(204次)及肌酐(221次)的测定,并作了相关比较。正常人(20名)唾液中尿素氮和肌酐的浓度分别为血液中的41.7%和45.2%。透析患者透析前唾液中尿素氮和肌酐的均值为血液中的59.7%和30.39%,透析后为22.2%和21.58%。病人唾液中尿素氮和肌酐的浓度在透析前后均同血中浓度呈正相关。作者认为唾液中尿素氮和肌酐的测定能反映其在血中的浓度,可使病人减少失血。

Since August 1981,urea nitrogen and creatinine in saliva and plasma were determined in 17 patients on chronic regular hcmodialysis.In normal persons the conccntra tions of urea nitrogen and creatinine in saliva were 47.7%and 45.2%of the concentrations in plasma respectively.The pre-dialysis mean values of salivary urea nitrogen and creatinine were 59.7%and 30.39%of that of plasma.Post-dialysis values dropped to 22.2%and 21.58%respectively.Statistical analysis of the data in the 17 patients showed that there was positive correlation between the urea nitrogen and creatinine concentrations in saliva and in plasma.Thus salivary urea nitrogen and creatinine dermination may reflect the levels in the blood.Blood loss for laboratory tests might be avoided in these cases.