高密度脂蛋白-胆固醇与冠心病

HIGH DENSITY LIPOPROTEIN CHOLESTEROL AND CORONARY HEART DISEASE

本文就我院116例冠心病患者所测定的血高密度脂蛋白-胆固醇(HDL-c)值及HDL-c与总胆固醇之比值(简称H/T),并随机选择了年龄与性别均与冠心病组对称的高血压病患者60例及100名健康人作为对照组,资料进行了分析和统计学处理。结果表明,不同年龄、性别的冠心病组其HDL-c与、H/T均明显低于其它两组(P<0.01).特别是异常H/T的发生率更明显高于其它两组,而高血压组和健康组之间无明显差别。本文资料支持HDL与冠心病呈负相关关系,同时,低于正常的H/T比值似乎可作为冠心病的一个危险因子。

High density lipoprotein cholesterol(HDL-C)blood level and the ratio between HDL-C and total cholesterol(H/T)were determined in 116 patients with coronary heart disease(CHD).Sixty randomly selected cases of essential hypertension over 45 and 100 healthy subjects,both sex and age matched,were taken as control groups.The results showed that the patients of all sex and age subgroups with CHD had significantly lower levels of HDL-C and H/T ratio as compared with those of the two control groups(p<0.01).The difference between the two control groups,however,was statistically insigni ficant.The data,thereby,support the view that the blood HDL-C concentration has a negative correlation with CHD risk.It seems that the H/T ratio below normal might be considered as a risk factor of CHD.