期刊文献+

组织相容性抗原Y测定鉴别真假两性畸形(附7例报告)

DETERMINATION OF HISTOCOMPATIBILITY ANTIGEN Y IN DIFFERENTIAL DIAGNOSIS OF TRUE AND FALSE HERMAPHRODITISM
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摘要 本文报道用精子毒性试验对7例两性畸形患者进行了组织相容性抗原Y(简称H-Y抗原)的测定,并结合核型和临床资料进行了分析和讨论. The histocompatibility antigen Y(H-Y antigen)was determined in 7 hermaphro-dites.In the 3 cases having Y chromosone,the H-Y gene became expressed,but not soin another 3 cases without Y chromosome.There was concordance between chromosomalconstitution and H-Y antigen in 6 cases,so there was normal primary sex differentia-tion.The abnormalities developed during the process of the secondary sex differentia-tion.One case was a H-Y antigen positive true hermaphrodite with abnormal primarysex differentiation.This patient was confirmed to have both the testis and ovary.Trueand false hermaphrodites can be identified by analysing karyotype and determining H-Yantigen together.
出处 《上海医学》 CAS 1982年第4期187-190,244,共5页 Shanghai Medical Journal
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